3-Pyrrolylpropylamine, also known as α-methyl-3-pyrrolylethylamine, is a chemical compound of the arylalkylamine family. It is the analogue of the serotonergic psychedelic α-methyltryptamine (AMT) in which the benzene component of the indole ring has been removed.
In contrast to tryptamines like AMT, 3-pyrrolylpropylamine does not bind to the serotonin 5-HT1A or 5-HT2A receptors (Ki = >10,000 nM). These findings suggest that the benzene part of the indole ring is required for significant binding serotonin receptors and by extension psychedelic activity. The activities of 3-pyrrolylpropylamine at other targets, such as the monoamine transporters, were not reported.
3-Pyrrolylpropylamine was first described in the scientific literature by at least 1990.
See also
- 3-Pyrrolylethylamine
- 2-Pyrrolylethylamine
References
External links
- 3-Pyrrolylpropylamine - Isomer Design
![CAS1311316423 3{Octahydropyrrolo[3,4c]pyrrol2ylmethyl}5](https://www.chemsrc.com/caspic/223/1311316-42-3.png)
